RNA,Small Interfering
《英文msh詞典》RNA,Small Interfering
[主題詞] RNA,Small Interfering
[同義詞] Small Interfering RNA
[同義詞] siRNA
[入口詞] Interfering RNA,Small
[英文釋義] Small ANTISENSE RNAs (20 -25 nucleotides) that are generated from specific dsRNAs (RNA,DOUBLE-STRANDED) which trigger targeted mRNA (RNA,MESSENGER) degradation (RNA INTERFERENCE). They serve as guides for the cleavage of homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. The same ribonuclease,Dicer,that is required for processing of the dsRNAs to siRNA is also involved in processing MICRORNAS (miRNAs) from their precursor RNAs.